Development of Multilayer Mesenchymal Stem Cell Cell Sheets

نویسندگان

چکیده

Cell and gene therapies have been developing dramatically over the past decade. To face adapt to development of these new therapies, Food Drug Administration (FDA) wrote updated guidelines from 2016 keep updating them. Mesenchymal stem cells (MSCs) are most used for treatment, far ahead induced pluripotent (iPSCs), based on registered clinical trials at clinicaltrials.gov. They widely because their differentiation capacity anti-inflammatory properties, but some controversies still require clear answers. Additional studies needed determine dosage, number, route injections (location transplantation method), if allogenic MSCs safe compared autologous MSC injection, including long-term effect. In this review, we summarize research our company is conducting with adipose stromal in engineering cell sheets potential application.

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ژورنال

عنوان ژورنال: International journal of translational medicine

سال: 2021

ISSN: ['2673-8937']

DOI: https://doi.org/10.3390/ijtm1010002